Compassion for Nature Developed by Science

In  vitro  Plant-tech  is  a  research  derived  company,  specialising  in  development and production of innovative active ingredients and extracts  using the plant  cell  cultivation technology. This  enables sustainable  production  of  uniform,  customised, high quality plant material for the Cosmetic, Nutraceutical and Pharmaceutical industries.

To ensure  maximum  effectiveness,  we  perform  a  science-based  plant selection. Our metabolic enhancement  platform  will result in an optimised  production and  high accumulation of  bioactive  substances.  All  our  extracts are standardised to concentration and activity.

CDMO services / In house developed extracts
CDMO services

Customised Client Exclusive Cell Lines and Extracts

Choose the plant or the properties you want to target and let us do the rest. We will help you select plants and develop  tailor made cell lines rich in bioactive components.

These   assignments   are   customised   according  to  your  needs.        Invitro  Plant-tech   will   act as  your  contract   development  and manufacturing  organisation (CDMO).  You  will own all intellectual property rights for the selected plant and developed cell lines.

In-house extracts and cell lines

Our Own Developed Extracts 

High quality and sustainable extracts, standardised to concentration and activity. We standardise our extracts to guarantee consistent quality and perform a science based plant selection to ensure superior extracts from plants that are safe to use, targeted metabolite composition and with high efficacy.

Rhodiola rosea (Roseroot) Plant Stem Cell Extract

Roseroot has been used since ancient times for its apoptogenic properties and was used by the Vikings to improve strength and endurance. The plant also has a positive effect on sensitive skin and improves over all skin conditions.

Our roseroot plant stem cell extract shows protecting and signaling activity on the dermis, and is rich in phenolics and flavonoids. A clinical study showed that the extract enhance skin radiance and general appearance of the skin, such as improved elasticity, firmness and reduction in wrinkles. The extract increases the gene activity of antioxidant enzymes and genes involved in cell structure.

Calendula officinalis (Pot Marigold) Petal Derived Callus Extract

Pot marigold was used by Ancient Egyptians to rejuvenate the skin. The flowers were also used to treat wounds, as an antiseptic and to promote healing. The plant has also been used to treat various skin ulcerations and eczema.

Our Calendula callus extract originates from the delicate petal tissue in the flower that has been almost fully dedifferentiated, which enables it to produce flower specific actives together with those produced by plant stem cells. The extract has strengthening, anti-oxidant and astringent properties, is rich in phenolics and contains scopoletin, a coumarin with interesting pharmacokenetic and rejuventaing properties. 

 Althaea officinalis (Marshmallow) Plant Stem Cell Extract

Althea comes from the Greek word “to cure” and officinalis means that it is used in medicine. The plant has been used since ancient times to treat inflammatory diseases, caught, mucous membrane irritation and wounds.

Our Althaea plant stem cell extract protects the skin and promotes cell rejuvenation. The extract is rich in phenolics and flavonoids, contains the flavonoid kaempferol, which has cytoprotective and photoprotective activities, and caffeic acid, which has been showed to increase the collagen production.

PS Protection, Aloe vera Plant Stem Cell Extract

Aloe vera, also known as "the gift from nature", was used by Cleopatra in her daily skin routine and is one of the most well known medicinal plants. The plant has soothing, moisturising and cooling properties.

Our Aloe plant stem cell extract is enriched with polysaccharides, which help support the skin immunity function. The extract has anti-pollution properties on dermal cells, where it protects the cells from the negative impact of pollutants, where it restores the oxidative stress balance and promotes cell rejuventation. The extract contains kaempferol, a flavinoid with cytoprotective and photoprotective properties.

In-house extracts and cell lines

“We are fascinated by plants and their unique ability to produce powerful active ingredients with beneficial effects. Through our sustainable plant cell cultivation platform, it  is  possible to produce  high  quality  plant extracts  with  care and compassion for nature."                                                                                                                           Anna Holefors PhD, Founder and CEO of In vitro Plant-tech AB

Plantago major (Greater Plantain) Plant Stem Cell Extract

Greater plantain is an old medicinal plant well known for its wound healing properties and to treat various skin disorders. The plant was used by the Vikings and has anti-inflammatory, antimicrobial, analgesic and antioxidant properties.

Our Plantago plant stem cell extract protects and strengthen the skin. A clinical study has verified that our Plantago plant stem cell extract improves the general appearance of the skin, such as improved elasticity, firmness and reduction in wrinkles. The extract is high in tannins, which helps improves skin apperance and rejuventation, and contains ferulic acid and Kaempferol, which .....

Silybum marianum (Milk thistle) Plant Stem Cell Extract

Milk thistle, also called blessed milk thistle, was described already by the Romans and Greeks and has been used for centuries against liver related diseases, boils, and skin diseases. The plant is also used as a cell protectant, for wound healing, treatment against acne, rosacea and to increase moisture.

Our milk thistle plant stem cell extract has strong antioxidant properties and a high content of phenolics, flavonoids, coumarins and ferulic acid. The extract also exhibit DNA protecting and anti-irritant properties.

Flower Power Innovation

Combines the power of plant stem cells with flower specific actives. This is a mixed extract consisting of the milk thistle plant stem cell extract and a flower derived callus extract from pot marigold, with protectant and rejuvenating properties.

Our flower power extract has protective and antioxidant properties. A clinical study has verified that the extract improves skin elasticity. The extract has a complex phenolic composition, is rich in flavonoids and contains scopoletin , kaemferol and salicylic acid.

Under Development

We are continuously working to establish new cell lines......


Reliable and Sustainable production

A large portion of plant raw material available on the market is still produced through traditional methods: harvesting of wild populations, field and greenhouse cultivation. It is estimated that about 70% of plant collections are performed by destructive harvesting, leading to endangerment of wild populations*. Field and greenhouse cultivation use large amounts of water and often includes usage of pesticides. Plant raw material produced in this way can also have low and varying quality.

Plant cell cultivation is a sustainable method that enables continous production, only requires a small part of one individual to build up a full population and therefore does not deplete the natural populations. No pesticides are used during production and it uses less water as compared to field cultivation. It is a continuous cultivation with full traceability and control, and is not affected by variations in weather or seasonal changes. Cell cultures are also often produced much faster and at a higher quality as compared with traditional cultivation in field. It also enables production of specific actives and to obatined an overall enriched production of metabolites.

*Report of the Task Force on Conservation & Sustainable use of Medicinal Plants, Government of India, Planning Commission, 2000

Quality and sustainability

Quality and Sustainability

We focus on having the best  products and assortment on  the market. Our  products are quality  assured  through  metabolic profiling, quantity of defined marker substances and microbial control. 
  • How to ensure high activity and availability of the active components in our extracts?

    When you prepare an expresso, you need to grind the beans and infuse the powder to release the flavours and actives. Likewise, in an extract the active components are made available and concentrated during the extraction process. Because of the roboust nature of the cell walls and organelles in plant cells, the active components are not always available unless an extraction process is performed. 

  • What does extract concentration mean?

    Similar to the fact that an expresso is a concentrated form of coffe, botanical extracts can be more or less concentrated. The concentration for extracts are often presented as mg dry extract/kg extract in carrier , where the carrier can be glycerol or similar. A 10% extract concentration will correspond to 100 mg dry extract/kg extract in carrier, whereas a 0.5% extract will correspond to 5 mg dry extract/kg extract in carrier. 

Quality and Sustainability
  • Why do we standardise our extracts?

    For botanical extracts it is important that the composition and activity is consistent. An extract that is standardised to activity will always have the same efficacy from batch to batch, ensuring reproducible results. For extracts that are not standardised to activity, there activity can vary over time. It is therefore important to perform standardisation both to concentration and activity.

  • How do we maximise sustainability?

    For us, ensuring sustainability is essential. We actively work with the three pillars of sustainability and are guided by Agenda 2030 and the Sustainable Development Goals (SDGs)**. We continuously improve and learn by 

    • selection of sustainable ingredients, sourcing and suppliers

    • optimisation of all assays and processes

    • using renewable enegry sources

    •  performing carbon footprint analysis

    • COSMOS certification of in house extracts 

    • selecting carbon neutral shipments

    • General guidance to SDG1-17 

    • In depth work regarding SDG4-Quality Education, 13-Climate Action and 15-Life on Land

    ** Diesendorf, 2000; Benn et al., 2014;

Quality and Sustainability
  • What is an active substance?

    An active substance is a molecule with a biological activity, such as antioxidant or antiinflammatory. Active substances can be incorporated into creams, liquids or tablets and used to treat specific ailments.

  • Why are plants so good at producting actives?

    Upon a rainy day we are able to go inside for protection. Unlike us plants are not able to move and therefore have to find other ways to respond to environmental changes and stress. Through evolution plants have adapted to produce a wide range of active subtances to help cope with stress and disease situations. Some actives have strong health beneficial, anti-inflammatory and regenerative properties, whereas other can have antimicrobial or anticancer properties.

    Different plants have evolved to produce different types of actives, where some will be specific to certain species. Furthemore, some of the actives will be produced in specific parts of the plant, such as leaves, flowers or roots.

  • What is a plant stem cell?

    A plant stem cell is a cell that is in the first development phase and has not yet started to differentiate. It will produce some actives that are specific to this developmental phase and some that are more general. The scientific name of a plant stem cells is undifferentiated callus cells. 

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Contact information

In vitro Plant-tech

Geijersgatan 4B, 216 18 Limhamn, Sweden

Geijersgatan 4B